Immunopharmacology 2018

Immuno Virology

Immunology is the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. Viruses are strongly immunogenic and induces 2 types of immune responses; humoral and cellular. The repertoire of specificities of T and B cells are formed by rearrangements and somatic mutations. T and B cells do not generally recognize the same epitopes present on the same virus. B cells see the free unaltered proteins in their native 3-D conformation whereas T cells usually see the Ag in a denatured form in conjunction with MHC molecules. The characteristics of the immune reaction to the same virus may differ in different individuals depending on their genetic constitutions.

·               Human and animal viral immunology

·               Immunological characterization of viral components

·               Pathogenic mechanisms

·               Virus-based immunological diseases, including autoimmune syndromes

·               Research and development of viral vaccines, including field trials

·               Viral diagnostics

·               Tumour and cancer immunology with virus as the primary factor

·               Viral immunology methods

·               EBOLA, FLU, HIV...